Restore, Rejuvenate, and Repair with Polynucleotides
Discover the next generation in skin regeneration—polynucleotide treatments work deep within the skin to repair cellular damage, boost hydration, and stimulate collagen for a smoother, firmer, and more youthful appearance.
Why Polynucleotides?
Polynucleotides are powerful biostimulators that work at a cellular level to repair tissue, improve skin elasticity, and deeply hydrate from within. Unlike traditional fillers, they enhance your skin’s natural regeneration process, making them ideal for treating fine lines, dullness, acne scars, and even under-eye concerns. Safe, natural, and effective—polynucleotides offer a subtle, long-lasting glow that restores skin health from the inside out.
How do Polynucleotides work?
Polynucleotides are naturally derived molecules that stimulate cell regeneration and repair. When injected into the skin, they activate fibroblasts—cells responsible for producing collagen and elastin—while also reducing inflammation and boosting hydration. This process supports tissue healing, improves skin structure, and restores elasticity, making your skin look firmer, smoother, and more radiant over time.
How Many Sessions are required?
Most clients benefit from a course of 3 sessions spaced 2–4 weeks apart, followed by maintenance treatments every 4–6 months. Results improve gradually as collagen production increases and skin regenerates naturally. Your practitioner will recommend a plan based on your skin’s needs and goals.
At a glance
Treatments needed
2-4
Price
From £180 per treatment
Treatment time
30 minutes
Recovery time
24-48 hours
Back to work
Immediately
How long it lasts
Who is it for?
Polynucleotide treatments are ideal for anyone looking to improve skin texture, firmness, and hydration—especially those with fine lines, dullness, acne scarring, under-eye concerns, or signs of aging. Suitable for all skin types, it’s a great option for those seeking natural, regenerative results without adding volume like traditional fillers.
Polynucleotides are suitable for a wide range of people & will treat:
• Fine lines and wrinkles
•Dull or tired-looking skin
•Acne scars and enlarged pores
•Dehydrated or dry skin
•Under-eye hollows and dark circles
•Skin laxity and loss of firmness
•Redness and inflammation
•Sun-damaged or uneven skin tone
What to expect
As with all treatments, your journey will begin with a consultation, where Jessica will take the time to understand your concerns and discuss your desired results.
Before & After
FREQUENTLY ASKED QUESTIONS
Polynucleotides are advanced skin regenerators that repair and rejuvenate the skin at a deep cellular level. They improve texture, boost elasticity, and enhance hydration, making them perfect for addressing fine lines, acne scars, under-eye concerns, sun damage, and general signs of aging. By stimulating collagen production and reducing inflammation, polynucleotides naturally restore a smoother, firmer, and more radiant complexion over time.
Polynucleotides and Botox serve different purposes, so whether one is “better” depends on your skincare goals.
•Polynucleotides focus on skin regeneration, improving skin texture, elasticity, hydration, and treating concerns like fine lines, acne scars, and under-eye issues. They work by stimulating collagen production and repairing skin at a cellular level, offering a natural, subtle rejuvenation over time.
•Botox, on the other hand, is used primarily for targeting dynamic wrinkles caused by muscle movement (like frown lines or crow’s feet). It works by temporarily paralyzing the muscles, preventing further wrinkle formation.
If your goal is skin regeneration and improving skin health, polynucleotides may be the better option. If you’re looking to target muscle-related wrinkles, Botox would be more effective. Many clients opt for both treatments, using Botox for dynamic wrinkles and polynucleotides for overall skin rejuvenation.
Yes, polynucleotides really work—and there’s growing clinical evidence and real-world results to support their effectiveness. They stimulate your skin’s natural healing processes by activating fibroblasts (the cells responsible for collagen and elastin production), improving skin quality, hydration, and elasticity over time. Many people see noticeable improvements in texture, firmness, and radiance after a few sessions.
However, results are gradual and subtle, not instant like fillers or Botox. They’re best for those seeking natural, long-term skin rejuvenation rather than dramatic or immediate changes.
Results from polynucleotide treatments typically last 6 to 9 months, depending on your skin type, lifestyle, and treatment area. Many clients choose to have maintenance sessions every 4–6 months to keep their skin looking fresh, hydrated, and youthful. Because the results build over time by boosting your skin’s natural regeneration, consistency is key for long-term improvement.
We apply local anaesthetic approximately 20 minutes prior to your treatment so you will experience very little pain or discomfort.
– Individual intolerance to the components of the meso cocktail
– Damage to the skin at the injection sites
– Clients with bleeding disorders and/or receiving anticoagulant treatment
– Fevers or any infectious diseases
– Oncological diseases
– Pregnancy and lactation
– Exacerbation of herpes infection
– Tendency to form keloids
– Autoimmune diseases (it is necessary to consult with your doctor)
– Avoid excessive sun exposure (including sunbeds)
– If necessary, use an SPF cream
– Avoid visiting public baths, saunas, gymnasiums, and fitness centers.
– Avoid using aggressive skin cleansers (scrubs, peels, brushes, and washcloths).
– Regularly apply an agent with anti-inflammatory and regenerating effects.
– Avoid scratching or rubbing the skin.
Price includes a full consultation
For more information or to book now please email info@perfectlyapplied.co.uk.